Science

Research from the Eli5a science team.

Peer-reviewed papers and preprints, 2024 to 2026. Preprints are labelled and have not been peer reviewed. Academic affiliations do not imply institutional endorsement.

2026

Perspectives: governing the rise of decentralized science and artificial intelligence in healthcare

Science and Public Policy · Journal article · 10.1093/scipol/scaf092

DENTAL IMPLANT FAILURE ASSOCIATED WITH ORTHOKERATINIZED ODONTOGENIC CYST: FIRST REPORTED CASE

Journal of Oral Implantology · Journal article · 10.1563/aaid-joi-D-26-00193

Comparative Evaluation of a New Autonomous AI Agent Versus Frontier LLMs for AI-Generated Patient Information Sheets on Pediatric Pathologies

Cancers · Journal article

Artificial intelligence-enhanced virtual reality for pathology education

Annals of Diagnostic Pathology · Journal article · 10.1016/j.anndiagpath.2026.152639

Potential oral and maxillofacial adverse events associated with glucagon-like peptide-1 receptor agonist administration: a narrative review.

Quintessence international (Berlin, Germany : 1985) · Journal article · 10.3290/j.qi.b7034788

Giant compound odontoma associated with a severely displaced mandibular canine: a case report.

General dentistry · Journal article

In Defense of AI as an 'Author' Ethical Implications for Scientific Authors, Reviewers, Editors, and Publishing Policies.

Head and neck pathology · Journal article · 10.1007/s12105-026-01924-0

Adenomatoid odontogenic tumor associated with impacted maxillary premolars: report of 2 cases.

General dentistry · Journal article

Spatial transcriptomics and artificial intelligence: a scoping review of emerging applications in head and neck pathology

Head and Neck Pathology · Journal article · 10.1007/s12105-025-01876-x

Incorporating critical assessment of emerging artificial intelligence tools into oral and maxillofacial pathology residency training.

Oral surgery, oral medicine, oral pathology and oral radiology · Journal article · 10.1016/j.oooo.2026.03.003

Histopathology and the standard of care.

General dentistry · Journal article

Painful and partially erupted odontoma: a case report.

General dentistry · Journal article

Novel Case of a Molecularly Confirmed Low-Grade Fibromyxoid Sarcoma of the Floor of the Mouth and Literature Review

Head and Neck Pathology · Journal article · 10.1007/s12105-026-01888-1

2025

Performance of AI Chatbots on Head and Neck Pathology Board-Style Exam Questions and Guidelines for Responsible Use.

Head and neck pathology · Journal article · 10.1007/s12105-025-01850-7

A rare manifestation of dental implant failure associated with sarcoidosis.

Journal of the American Dental Association (1939) · Journal article · 10.1016/j.adaj.2025.10.006

Classifying histological images using cell counting estimators

2025 IEEE 14th International Conference on Consumer Electronics - Berlin (ICCE-Berlin) · Journal article · 10.1109/icce-berlin67488.2025.11277969

Advancing homebrew AI in diagnostic practice: opportunities and barriers†.

The Journal of pathology · Journal article · 10.1002/path.6483

Osteoporotic bone marrow defect mimicking odontogenic cysts: report of 2 cases.

General dentistry · Journal article

Oral mucosal adverse events following administration of an immune checkpoint inhibitor: a case report.

General dentistry · Journal article

Decentralized Science Artificial Intelligence (DeSci AI): Barriers and Opportunities for Mass Adoption by the Scientific Community

· Preprint · 10.31235/osf.io/hg4ds_v1

AI-generated podcasts for health education.

Medical teacher · Journal article

Osteosarcoma Arising in Noonan Syndrome/RASopathy Complex: First Case Report.

Head and neck pathology · Journal article · 10.1007/s12105-025-01762-6

Alpha-gal syndrome: potential for a hypersensitivity reaction after the use of dental products: Literature review and case report.

Journal of the American Dental Association (1939) · Journal article · 10.1016/j.adaj.2025.04.001

Secondary syphilis of the floor of the mouth masquerading as squamous cell carcinoma: a case report.

General dentistry · Journal article

Gingival odontogenic keratocyst presenting as pseudoinfection: Inclusion of demonstrative case report and review.

Clinical advances in periodontics · Journal article · 10.1002/cap.10350

Emergency of oral haemorrhage: Retrospective study over 2 years

Oral Diseases · Journal article · 10.1111/odi.15137

A Scoping Review of Infrared Spectroscopy and Machine Learning Methods for Head and Neck Precancer and Cancer Diagnosis and Prognosis

Cancers · Journal article · 10.3390/cancers17050796

The Development and Functionality of Eli5a: An Autonomous Superintelligent AI Agent for Simplifying Scientific Research for the General Public

· Preprint · 10.62891/1a85f48e

Hyperpigmentation of the oral mucosa caused by dietary beta carotene: a case report.

General dentistry · Journal article

Efficacy and empathy of AI chatbots in answering frequently asked questions on oral oncology.

Oral surgery, oral medicine, oral pathology and oral radiology · Journal article · 10.1016/j.oooo.2024.12.028

Case Use Demonstration and Superior Image Generation Capabilities of Eli5a: An Autonomous Superintelligent AI Agent for Simplifying Scientific Research for the General Public

· Preprint · 10.62891/a1791016

2024

SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis.

PLoS pathogens · Journal article · 10.1371/journal.ppat.1012375

Fluid-filled blisters with background white striations.

Journal of the American Dental Association (1939) · Journal article · 10.1016/j.adaj.2024.08.011

Recurrent peripheral odontogenic keratocyst: Review of the literature and presentation of a novel case initially masquerading as an atypical infected lateral periodontal cyst

Journal of Stomatology, Oral and Maxillofacial Surgery · Journal article · 10.1016/j.jormas.2023.101540

Deep Learning-Based Image Classification and Segmentation on Digital Histopathology for Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · Journal article · 10.1111/jop.13578

Anti-HDGF Antibody Targets EGFR Tyrosine Kinase Inhibitor-Tolerant Cells in NSCLC Patient-Derived Xenografts.

Cancer research communications · Journal article · 10.1158/2767-9764.crc-24-0020

Responsible artificial intelligence for addressing equity in oral healthcare.

Frontiers in oral health · Journal article · 10.3389/froh.2024.1408867

Oral Microbiota Alterations in Subjects with SARS-CoV-2 Displaying Prevalence of the Opportunistic Fungal Pathogen Candida albicans

Microorganisms · Journal article · 10.3390/microorganisms12071356

Detection of extracranial and intracranial calcified carotid artery atheromas in cone beam computed tomography using a deep learning convolutional neural network image segmentation approach

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology · Journal article · 10.1016/j.oooo.2023.08.009

Rare nonsyndromic recurrent solitary gingival neurofibroma in an older adult

Clinical Advances in Periodontics · Journal article · 10.1002/cap.10260

Florid follicular lymphoid hyperplasia of the palate: review of the literature and report of an illustrative case.

Quintessence international (Berlin, Germany : 1985) · Journal article · 10.3290/j.qi.b5316965

Does Candida auris colonize the oral cavity? A retrospective institutional experience

Oral Diseases · Journal article · 10.1111/odi.14720

Deep learning for temporomandibular joint arthropathies: A systematic review and meta-analysis.

Journal of oral rehabilitation · Journal article · 10.1111/joor.13701

An Update on the Use of Artificial Intelligence in Digital Pathology for Oral Epithelial Dysplasia Research.

Head and neck pathology · Journal article · 10.1007/s12105-024-01643-4

370 Point-of-Service Salivary Microbiome Analysis in the Prevention and Detection of Oral Premalignant Lesions

Journal of clinical and translational science · Journal article

Oral manifestations of mpox (monkeypox).

General dentistry · Journal article

Oral epithelial dysplasia with lymphocytic immune response: clinicopathological characterisation of 44 cases.

Histopathology · Journal article · 10.1111/his.15171

Dental implant failure possibly attributed to embedded pencil graphite: first clinical report.

General dentistry · Journal article

Performance of AI Chatbots on Controversial Topics in Oral Medicine, Pathology, and Radiology

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology · Journal article · 10.1016/j.oooo.2024.01.015

A Longitudinal Metagenomic Comparative Analysis of Oral Microbiome Shifts in Patients Receiving Proton Radiation versus Photon Radiation for Head and Neck Cancer.

Journal of cancer & allied specialties · Journal article · 10.37029/jcas.v10i1.579

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Research from the Eli5a science team.

2026

Perspectives: governing the rise of decentralized science and artificial intelligence in healthcare

DENTAL IMPLANT FAILURE ASSOCIATED WITH ORTHOKERATINIZED ODONTOGENIC CYST: FIRST REPORTED CASE

Comparative Evaluation of a New Autonomous AI Agent Versus Frontier LLMs for AI-Generated Patient Information Sheets on Pediatric Pathologies

Artificial intelligence-enhanced virtual reality for pathology education

Potential oral and maxillofacial adverse events associated with glucagon-like peptide-1 receptor agonist administration: a narrative review.

Giant compound odontoma associated with a severely displaced mandibular canine: a case report.

In Defense of AI as an 'Author' Ethical Implications for Scientific Authors, Reviewers, Editors, and Publishing Policies.

Adenomatoid odontogenic tumor associated with impacted maxillary premolars: report of 2 cases.

Spatial transcriptomics and artificial intelligence: a scoping review of emerging applications in head and neck pathology

Incorporating critical assessment of emerging artificial intelligence tools into oral and maxillofacial pathology residency training.

Histopathology and the standard of care.

Painful and partially erupted odontoma: a case report.

Novel Case of a Molecularly Confirmed Low-Grade Fibromyxoid Sarcoma of the Floor of the Mouth and Literature Review

2025

Performance of AI Chatbots on Head and Neck Pathology Board-Style Exam Questions and Guidelines for Responsible Use.

A rare manifestation of dental implant failure associated with sarcoidosis.

Classifying histological images using cell counting estimators

Advancing homebrew AI in diagnostic practice: opportunities and barriers†.

Osteoporotic bone marrow defect mimicking odontogenic cysts: report of 2 cases.

Oral mucosal adverse events following administration of an immune checkpoint inhibitor: a case report.

Decentralized Science Artificial Intelligence (DeSci AI): Barriers and Opportunities for Mass Adoption by the Scientific Community

AI-generated podcasts for health education.

Osteosarcoma Arising in Noonan Syndrome/RASopathy Complex: First Case Report.

Alpha-gal syndrome: potential for a hypersensitivity reaction after the use of dental products: Literature review and case report.

Secondary syphilis of the floor of the mouth masquerading as squamous cell carcinoma: a case report.

Gingival odontogenic keratocyst presenting as pseudoinfection: Inclusion of demonstrative case report and review.

Emergency of oral haemorrhage: Retrospective study over 2 years

A Scoping Review of Infrared Spectroscopy and Machine Learning Methods for Head and Neck Precancer and Cancer Diagnosis and Prognosis

The Development and Functionality of Eli5a: An Autonomous Superintelligent AI Agent for Simplifying Scientific Research for the General Public

Hyperpigmentation of the oral mucosa caused by dietary beta carotene: a case report.

Efficacy and empathy of AI chatbots in answering frequently asked questions on oral oncology.

Case Use Demonstration and Superior Image Generation Capabilities of Eli5a: An Autonomous Superintelligent AI Agent for Simplifying Scientific Research for the General Public

2024

SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis.

Fluid-filled blisters with background white striations.

Recurrent peripheral odontogenic keratocyst: Review of the literature and presentation of a novel case initially masquerading as an atypical infected lateral periodontal cyst

Deep Learning-Based Image Classification and Segmentation on Digital Histopathology for Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Anti-HDGF Antibody Targets EGFR Tyrosine Kinase Inhibitor-Tolerant Cells in NSCLC Patient-Derived Xenografts.

Responsible artificial intelligence for addressing equity in oral healthcare.

Oral Microbiota Alterations in Subjects with SARS-CoV-2 Displaying Prevalence of the Opportunistic Fungal Pathogen Candida albicans

Detection of extracranial and intracranial calcified carotid artery atheromas in cone beam computed tomography using a deep learning convolutional neural network image segmentation approach

Rare nonsyndromic recurrent solitary gingival neurofibroma in an older adult

Florid follicular lymphoid hyperplasia of the palate: review of the literature and report of an illustrative case.

Does Candida auris colonize the oral cavity? A retrospective institutional experience

Deep learning for temporomandibular joint arthropathies: A systematic review and meta-analysis.

An Update on the Use of Artificial Intelligence in Digital Pathology for Oral Epithelial Dysplasia Research.

370 Point-of-Service Salivary Microbiome Analysis in the Prevention and Detection of Oral Premalignant Lesions

Oral manifestations of mpox (monkeypox).

Oral epithelial dysplasia with lymphocytic immune response: clinicopathological characterisation of 44 cases.

Dental implant failure possibly attributed to embedded pencil graphite: first clinical report.

Performance of AI Chatbots on Controversial Topics in Oral Medicine, Pathology, and Radiology

A Longitudinal Metagenomic Comparative Analysis of Oral Microbiome Shifts in Patients Receiving Proton Radiation versus Photon Radiation for Head and Neck Cancer.

Bring us a scientific question.

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